Postcentral gyrus

Brain: Postcentral gyrus
Postcentral gyrus of the human brain.
Brodmann areas 3, 1 and 2 of human brain. Brodmann area 3 is in red, area 1 in green, and area 2 in yellow.
Latin Gyrus postcentralis
Gray's subject #189 823
NeuroNames hier-87
NeuroLex ID birnlex_1070

The lateral postcentral gyrus is a prominent structure in the parietal lobe of the human brain and an important landmark. It is the location of primary somatosensory cortex, the main sensory receptive area for the sense of touch. Like other sensory areas, there is a map of sensory space in this location, called the sensory homunculus.

The primary somatosensory cortex was initially defined from surface stimulation studies of Wilder Penfield, and parallel surface potential studies of Bard, Woolsey, and Marshall. Although initially defined to be roughly the same as Brodmann areas 3, 1 and 2, more recent work by Kaas has suggested that for homogeny with other sensory fields only area 3 should be referred to as "primary somatosensory cortex", as it receives the bulk of the thalamocortical projections from the sensory input fields.

Contents

Postcentral gyrus

The lateral postcentral gyrus is bounded by:

Brodmann areas 3, 1 and 2

Brodmann areas 3, 1 and 2 make up the primary somatosensory cortex of the human brain (or S1). Because Brodmann sliced the brain somewhat obliquely, he encountered area 1 first; however, from rostral to caudal the Brodmann designations are 3, 1 and 2, respectively.

Brodmann area 3 is subdivided into area 3a and 3b. Where BA 1 occupies the apex of the postcentral gyrus, the rostral border of BA 3a is in the nadir of the Central sulcus, and is caudally followed by BA 3b, then BA 1, with BA 2 following and ending in the nadir of the postcentral sulcus. BA 3b is now conceived as the primary somatosensory cortex because 1) it receives dense inputs from the NP nucleus of the thalamus; 2) its neurons are highly responsive to somatosensory stimuli, but not other stimuli; 3) lesions here impair somatic sensation; and 4) electrical stimulation evokes somatic sensory experience. BA 3a also receives dense input from the thalamus; however, this area is concerned with proprioception.

Areas 1 and 2 receive dense inputs from BA 3b. The projection from 3b to 1 primarily relays texture information; the projection to area 2 emphasizes size and shape. Lesions confined to these areas produce predictable dysfunction in texture, size, and shape discrimination.

Somatosensory cortex, like other neocortex, is layered. Like other sensory cortex (i.e. visual and auditory) the thalamic inputs project into layer IV, which in turn project into other layers. Also like other sensory cortices, S1 neurons are grouped together with similar inputs and responses into vertical columns that extend across cortical layers (e.g. As shown by Vernon Mountcastle, into alternating layers of slowly adapting and rapidly adapting neurons; or spatial segmentation of the vibrissae on mouse/rat cerebral cortex).

This area of cortex, as shown by Wilder Penfield and others, is organized somatotopically, having the pattern of a homunculus. That is, the legs and trunk fold over the midline; the arms and hands are along the middle of the area shown here; and the face is near the bottom of the figure. While it is not well-shown here, the lips and hands are enlarged on a proper homunculus, since a larger number of neurons in the cerebral cortex are devoted to processing information from these areas.

The positions of Brodmann area's 3, 1 and 2 are - from the nadir of the central sulcus towards the apex of the postcentral gyrus - 3a, 3b, 1, and 2 respectively.

These areas contain cells that project to the secondary somatosensory cortex.

Clinical significance

Lesions affecting the primary somatosensory cortex produce characteristic symptoms including: agraphesthesia, astereognosia, loss of vibration, proprioception and fine touch (because the third-order neuron of the medial-lemniscal pathway cannot synapse in the cortex). It can also produce hemineglect, if it affects the non-dominant hemisphere.

It could also reduce nociception, thermoception and crude touch, but since information from the spinothalamic tract is interpreted mainly by other areas of the brain (see insular cortex and cingulate gyrus), it is not as relevant as the other symptoms.

See also

Additional images

External links